As a synthetic organic chemistry group, we are dedicated to addressing enduring synthetic challenges and developing transformative reactions with the aid of transition-metal and organocatalysts. With these new methods, our goal is to readily derivatize natural products and biologically active small molecules at late stages with controllable selectivities.

At the heart of our research interests is the innovation of strategies to introduce new functional groups, facilitating rapid access to derivatives of medicinally interesting compounds. We are especially interested in harnessing non-covalent interactions pivotal in enzymatic reactions for designing small-molecule catalysts that promote challenging transformations, as well as developing new approaches to enhance these types of interactions for biologically active compounds. Members of the Feng group will develop expertise in areas including organic synthesis, asymmetric catalysis, and organometallic chemistry.

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